THE PIPELINE

Advancing the first
Fas Ligandblocking antibody in the clinic

M3T01 is a first-in-class fully human IgG4/Kappa monoclonal antibody that binds fas ligand (FasL) with picomolar affinity and potently inhibits FasL-mediated apoptosis of T cells.

TRIAL

Accelerating our progress to market viability

A phase I clinical trial is currently underway (NCT06719362) evaluating M3T01 in patients with advanced solid tumors. M3T01 is being tested as a single agent and in combination with pembrolizumab and other cancer therapies.

Program
Program

Program

M3T01
FasL Inhibitor

M3T01 FasL Inhibitor

M3T01
FasL Inhibitor

Indication
Indication

Indication

Solid tumors

Solid tumors

Region
Region

Region

US

US

Discovery
Discovery (Complete)

Discovery

Preclinical
Preclinical (Complete)

Preclinical

Phase 1
Phase 1 (In Progress)

Phase 1

Phase 2
Phase 2 (Upcoming)

Phase 2

Phase 3
Phase 3 (Upcoming)

Phase 3

What'S NEXT

Looking ahead &
strategic partnerships

Looking ahead &
strategic partnerships

Partnering to Expand the Potential of FasL Blockade

Gamma Biotherapeutics is actively seeking investors and collaborators to advance M3T01 and explore new indications where protecting T cells could redefine treatment outcomes.

Co-Development Opportunities

We welcome partnerships in solid tumors, hematologic malignancies, and combination immunotherapies where FasL blockade may enhance therapeutic efficacy and durability.

The Trial

Contact us to inquire about the clinical trial, explore partnerships, investment, or to learn more.

The Trial

Contact us to inquire about the clinical trial, explore partnerships, investment, or to learn more.

The Trial

Contact us to inquire about the clinical trial, explore partnerships, investment, or to learn more.